Skip to main content

AMD Instinct MI300X vs AMD Instinct MI325X: Spec Comparison & Buyer's Guide

In AI infrastructure selection, AMD Instinct MI300X and AMD Instinct MI325X are two accelerators frequently compared. This article contrasts them item by item — architecture, compute, memory, power, and release cadence — to help you quickly judge which fits training or inference workloads.

Spec Comparison Table​

VendorAMD Instinct MI300XAMD Instinct MI325X
VendorAMDAMD
ArchitectureCDNA 3CDNA 3
ProcessTSMC 5nm + 6nm—
Release Date2023-06-132024-10-10
FP8 Compute——
FP16 Compute——
FP32 Compute65.3 TFLOPS—
INT8 Compute——
Memory Type——
Memory Capacity192 GB HBM3256 GB HBM3e
Memory Bandwidth5,300 GB/s6.48 TB/s
TDP Power750 W750 W

Key Differences​

  • Memory capacity: AMD Instinct MI325X packs 256 GB HBM3e, more than AMD Instinct MI300X's 192 GB HBM3, more comfortable for single-card hosting of very large models.

Selection Advice​

  • When chasing extreme single-card compute and a mature toolchain, prioritize AMD Instinct MI300X; if budget, power wall, or local support are hard constraints, AMD Instinct MI325X often fits better. Use this site's AI Compute Card Comparison Tool to validate multiple chips side-by-side before deciding.

FAQ​

What are the main differences between AMD Instinct MI300X and AMD Instinct MI325X?​

The core difference is architecture and compute density: AMD Instinct MI300X uses CDNA 3, FP8 ~No public FP8 data, memory 192 GB HBM3; AMD Instinct MI325X uses CDNA 3, FP8 ~No public FP8 data, memory 256 GB HBM3e. See the comparison table above.

What is the TDP (power) of AMD Instinct MI300X?​

AMD Instinct MI300X has a TDP of 750 W; actual whole-system power also includes board, fans, and PUE.

Which is better for large-model training / inference?​

Training values memory capacity, bandwidth, and multi-card interconnect; inference values single-card throughput and power efficiency. Combine the "Key Differences" and "Selection Advice" above with your batch size, model size, and SLA.

How much do AMD Instinct MI300X and AMD Instinct MI325X differ in memory capacity?​

AMD Instinct MI300X is 192 GB HBM3, AMD Instinct MI325X is 256 GB HBM3e; the gap directly affects loadable model size and context length.